Cellular Responses to Mechanical Stress Selected Contribution: A three-dimensional model for assessment of in vitro toxicity in Balaena mysticetus renal tissue
نویسندگان
چکیده
T. J. GOODWIN, L. COATE-LI, R. M. LINNEHAN, AND T. G. HAMMOND Cellular Biotechnology Program, Flight Definition/Cell Biology, National Aeronautics and Space Administration, Johnson Space Center, Wyle Laboratories, Life Sciences-Systems and Services, and Flight Crew Operations, National Aeronautics and Space Administration, Johnson Space Center, Houston, Texas 77058; and Tulane Environmental Astrobiology Center, Nephrology Section SL-45, Tulane University Medical Center and Veterans Administration Medical Center, New Orleans, Louisiana 70112
منابع مشابه
Selected contribution: a three-dimensional model for assessment of in vitro toxicity in balaena mysticetus renal tissue.
This study established two- and three-dimensional renal proximal tubular cell cultures of the endangered species bowhead whale (Balaena mysticetus), developed SV40-transfected cultures, and cloned the 61-amino acid open reading frame for the metallothionein protein, the primary binding site for heavy metal contamination in mammals. Microgravity research, modulations in mechanical culture condit...
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